Proteasome subunit alpha type-1 Antibody (PSMA1) | F43982-0.08ML

Proteasome subunit alpha type-1 Antibody (PSMA1) | F43982-0.08ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: WB, ELISA

Buffer: N/A

Limitation: This PSMA1 antibody is available for research use only.

Purity: Antigen affinity

Description: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Immunogen: A portion of amino acids 234-262 from the human protein was used as the immunogen for this PSMA1 antibody.

Storage: Aliquot the PSMA1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.