PIP5K1B Polyclonal Antibody | E-AB-65557

PIP5K1B Polyclonal Antibody | E-AB-65557 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: IF

Research Area: Signal Transduction

Background: Phosphatidylinositol-4-phosphate-5-kinase (PIPK) synthesizes phosphatidylinositol-4, 5-bisphosphate, which regulates various processes including cell proliferation, survival, membrane trafficking, and cytoskeletal organization. The PIPK family is divided into type I, type II and type III . Each type of the PIPK family phosphorylate distinct substrates and they contain an activation loop, which determines their enzymatic specificity and subcellular targeting . The phosphatidylinositol-4-phosphate-5-kinase type I consists of three members, PIPK I, ∫, and, which are characterized by phosphorylating PI4P on the 5-hydroxyl . PIPK I (designated PIPK I ∫ in mouse) is expressed in brain tissue . PIPK I ∫, designated PIPK I a in mouse, is also called STM7. PIPK I has two variants produced by alternative splicing which are expressed in lung, brain, and kidneys.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human PIP5K1B (NP_003549.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification: Affinity purification

Dilution: IF 1:50-1:200

Conjugation: Unconjugated

Calculated Molecular Weight: N/A

Observed Molecular Weight: N/A

Clonality: N/A