Phospho-JAK3 (Tyr785) Polyclonal Antibody | E-AB-21215

Phospho-JAK3 (Tyr785) Polyclonal Antibody | E-AB-21215 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IHC-p, ELISA

Research Area: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Background: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthesized peptide derived from human JAK3 around the phosphorylation site of Tyr785

Buffer: PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4

Purification: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000

Conjugation: Unconjugated

Calculated Molecular Weight: 125 kDa

Observed Molecular Weight: 125 kDa

Clonality: Polyclonal