Phospho-ERK1/2 Antibody (Thr202/Tyr204) | F54044-0.1ML

Phospho-ERK1/2 Antibody (Thr202/Tyr204) | F54044-0.1ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Antibody in PBS with 50% Glycerol and 0.03% ProClin 300

Format: Purified

Clone: 2E8-2F6-C12

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human, Mouse

Application: WB

Buffer: N/A

Limitation: This phospho-ERK1/2 antibody is available for research use only.

Purity: Protein G affinity

Description: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.

Immunogen: A synthetic peptide corresponding to the amino acids surrounding pThr202 and pTyr204 of human ERK1/2 was used as the immunogen for this phospho-ERK1/2 antibody.

Storage: Store the phospho-ERK1/2 antibody at -20 °C.