Description
Phospho-ERK1/2 Antibody (Thr202/Tyr204) | F54044-0.1ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Antibody in PBS with 50% Glycerol and 0.03% ProClin 300
Format: Purified
Clone: 2E8-2F6-C12
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human, Mouse
Application: WB
Buffer: N/A
Limitation: This phospho-ERK1/2 antibody is available for research use only.
Purity: Protein G affinity
Description: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements.
Immunogen: A synthetic peptide corresponding to the amino acids surrounding pThr202 and pTyr204 of human ERK1/2 was used as the immunogen for this phospho-ERK1/2 antibody.
Storage: Store the phospho-ERK1/2 antibody at -20 °C.
