Description
PE-Labeled Human HLA-A*24:02&B2M&p53 (TYSPALNKMF) Tetramer Protein | HLP-HP2Hc-25ug| Gentaur Distribution US, UK & Europe
TP53 has been recognized as a tumor suppressor. 50% of cancers carry a TP53 mutation while many others affect other pathway components. High-copy numbers of WT p53 peptide-MHC class I complexes were detected on tumor cells as compared to low copies on normal cells. The Human HLA-A*0201 p53 (GLAPPQHLIRV) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M, and GLAPPQHLIRV peptide of the p53.
Source: PE-Labeled Human HLA-A*24:02&B2M&p53 (TYSPALNKMF) Tetramer Protein (HLP-HP2Hc) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ile 305 (HLA-A*24:02) & Ile 21 - Met 119 (B2M) & TYSPALNKMF peptide (Accession # AAA59600.1 (HLA-A*24:02) & P61769 (B2M) & TYSPALNKMF).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Gly 25 - Ile 305 (HLA-A*24:02) & Ile 21 - Met 119 (B2M) & TYSPALNKMF peptide.
Conjugate: PE Labeled.
Molecular Weight: 35.8 kDa and 11.7 kDa.
Characteristics: PE-Labeled Human HLA-A*24:02&B2M&p53 (TYSPALNKMF) Tetramer Protein is assembled by biotinylated monomer (HLP-H82Eb) and PE-labeled streptavidin. Biotinylated Human HLA-A*24:02&B2M&p53 (TYSPALNKMF) Complex Protein is produced by co-expression of HLA and B2M loaded with p53 peptide. Biotinylated Human HLA-A*24:02&B2M&p53 (TYSPALNKMF) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).
Purity: 90%.
Buffer: PBS, 1% BSA, pH7.4.
Storage Conditions: -20℃, aviod light.
Shipping Conditions: RT
