PCNA Antibody (Proliferating Cell Nuclear Antigen) | F52380-0.4ML

PCNA Antibody (Proliferating Cell Nuclear Antigen) | F52380-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: 1157CT1.1.3

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human, Mouse, Rat

Application: IHC, WB, ELISA

Buffer: N/A

Limitation: This PCNA antibody is available for research use only.

Purity: Purified

Description: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.

Immunogen: A portion of amino acids 236-261 from human Proliferating Cell Nuclear Antigen was used as the immunogen for this PCNA antibody.

Storage: Aliquot the PCNA antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.