Description
PCNA Antibody (Proliferating Cell Nuclear Antigen) | F52380-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: 1157CT1.1.3
Host Animal: Mouse
Clonality: Monoclonal (mouse origin)
Species Reactivity: Human, Mouse, Rat
Application: IHC, WB, ELISA
Buffer: N/A
Limitation: This PCNA antibody is available for research use only.
Purity: Purified
Description: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
Immunogen: A portion of amino acids 236-261 from human Proliferating Cell Nuclear Antigen was used as the immunogen for this PCNA antibody.
Storage: Aliquot the PCNA antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
