Pan Cytokeratin Antibody Cocktail (Acidic + Basic) | V2330PE-100T

Pan Cytokeratin Antibody Cocktail (Acidic + Basic) | V2330PE-100T | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: PE Conjugate

Clone: AE1 + AE3

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human, Mouse, Rat

Application: FACS, IF

Buffer: N/A

Limitation: This pan Cytokeratin antibody AE1 + AE3 is available for research use only.

Purity: Protein G affinity chromatography

Description: Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI <5.7) and basic (pI >6.0) subfamilies. This pan keratin antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which include CK1, CK3-6, CK8, CK10, CK14-16, and CK19. Many studies have shown the usefulness of cytokeratin markers in cancer research and tumor diagnosis. The AE1 + AE3 antibody cocktail is a broad spectrum pan cytokeratin antibody cocktail which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It has been used to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. It stains cytokeratin present in normal and abnormal human tissues and has shown high sensitivity in the recognition of epithelial cells and carcinomas.

Immunogen: Human epidermal keratin was used as the immunogen for this pan Cytokeratin antibody.

Storage: Store the pan Cytokeratin antibody at 2-8oC. Conjugate is light sensitive, store in the dark.