p73 Antibody / Tumor Protein 73 | V8089-100UG

p73 Antibody / Tumor Protein 73 | V8089-100UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: P73/2531

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This p73 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: The p53 gene is a widely studied anti-oncogene, or tumor suppressor gene. The p53 gene product can act as a negative regulator of cell growth in response to DNA damage. Mutations and allelic loss of the p53 gene have been associated with malignant transformation in a wide variety of human tumors. p53 shares considerable sequence similarity with p73, a gene that maps to a region in chromosome 1 that is frequently deleted in neuroblastomas. However, p73 does not appear to be activated by DNA damaging agents.

Immunogen: A recombinant full-length human protein was used as the immunogen for this p73 antibody.

Storage: Store the p73 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).