OX40 Antibody / CD134 | V7534IHC-7ML

OX40 Antibody / CD134 | V7534IHC-7ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*

Format: Purified

Clone: OX40/3108

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This OX40 antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: This MAb recognizes a protein of 43kDa, identified as OX40, which is also known as CD134. OX40 is a type I integral membrane glycoprotein and member of the tumor necrosis factor/nerve growth factor receptor (TNFR/NGFR) family. It is expressed on activated T lymphocytes, hematopoietic precursor cells and fibroblasts. It functions as a T cell co-stimulatory receptor when bound by OX40 Ligand / TNFSF4 that is expressed by antigen presenting cells. OX40 thereby plays roles in T-cell activation as well as the regulation of differentiation, proliferation or apoptosis of normal and malignant lymphoid cells. OX40 is upregulated at the sites of inflammation, especially in case of multiple sclerosis and psoriatic lesions.

Immunogen: A portion of amino acids 95-205 from the human protein was used as the immunogen for the OX40 antibody.

Storage: Store the OX40 antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).