Description
MRP1 Antibody / ABCC1 | F49725-0.4ML | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human
Application: FACS, WB, ELISA
Buffer: N/A
Limitation: This MRP1 antibody is available for research use only.
Purity: Purified
Description: ABCC1, also called Multidrug resistance-associated protein 1 (MRP1) is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC gene are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts.
Immunogen: A portion of amino acids 1247-1275 from the human protein was used as the immunogen for this MRP1 antibody.
Storage: Aliquot the MRP1 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
