(KO Validated) POR Polyclonal Antibody | E-AB-62876

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SKU:
575-E-AB-62876
Size:
120 μL
€1,056.00
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Description

(KO Validated) POR Polyclonal Antibody | E-AB-62876 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IHC, IF

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction

Background: This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.

Lead Time: 7~10 days

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human POR (NP_000932.3).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification: Affinity purification

Dilution: WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:200

Conjugation: Unconjugated

Calculated Molecular Weight: 76 kDa

Observed Molecular Weight: 77 kDa

Clonality: N/A

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