Inhibin beta B chain Antibody / INHBB | F54580-0.4ML

Inhibin beta B chain Antibody / INHBB | F54580-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse

Application: IHC-P, WB

Buffer: N/A

Limitation: This Inhibin beta B chain antibody is available for research use only.

Purity: Antigen affinity purified

Description: The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.

Immunogen: A portion of amino acids 369-397 from the human protein was used as the immunogen for the Inhibin beta B chain antibody.

Storage: Aliquot the Inhibin beta B chain antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.