IL-12 Antibody | F51357-0.4ML

IL-12 Antibody | F51357-0.4ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In 1X PBS, pH 7.4, with 0.09% sodium azide

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human

Application: FACS, WB, IHC, ELISA

Buffer: N/A

Limitation: This IL-12 antibody is available for research use only.

Purity: Antigen affinity

Description: IL12A is a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity.

Immunogen: A portion of amino acids 168-195 from the human protein was used as the immunogen for this IL-12 antibody.

Storage: Aliquot the IL-12 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.