IL-10RA Antibody / IL-10R1 | V8346-20UG

IL-10RA Antibody / IL-10R1 | V8346-20UG | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Format: Purified

Clone: 1B1.3a

Host Animal: Rat

Clonality: Monoclonal (rat origin)

Species Reactivity: Mouse

Application: FACS

Buffer: N/A

Limitation: This IL-10RA antibody is available for research use only.

Purity: Protein G affinity chromatography

Description: This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110KDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation.

Immunogen: Purified recombinant extracellular region of mouse IL10RA was used as the immunogen for the IL-10RA antibody.

Storage: Store the IL-10RA antibody at 2-8oC (with azide) or aliquot and store at -20 °C or colder (without azide).