Human TROP-2 / TACSTD2 (88-274) Protein, His Tag | TR2-H52H6-100ug

Human TROP-2 / TACSTD2 (88-274) Protein, His Tag | TR2-H52H6-100ug| Gentaur Distribution US, UK & Europe

TROP-2 is a single-copy gene in human cells, and encodes a type-1 transmembrane glycoprotein which is over-expressed in various malignancies, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1. TROP-2 is related to epithelial cell adhesion molecule (EpCAM), also called TROP-1, gp40, and KSA. Trop-1 and Trop-2 are homologous to serum IGF-II-binding proteins and appear as signal transducers. Thus, they likely represent novel cell-surface receptors and may play a role in regulating the growth of carcinoma cells.

Source: Human TROP-2 (88-274) Protein, His Tag (TR2-H52H6) is expressed from human 293 cells (HEK293). It contains AA Thr 88 - Thr 274 (Accession # P09758-1).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Thr 88 - Thr 274.

Conjugate: Unconjugated.

Molecular Weight: 23.5 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 23.5 kDa. The protein migrates as 33-43 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT