Human TNF-beta / Lymphotoxin-alpha Protein, His Tag (MALS verified) | TNB-H52H3-1mg

Human TNF-beta / Lymphotoxin-alpha Protein, His Tag (MALS verified) | TNB-H52H3-1mg| Gentaur Distribution US, UK & Europe

The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene.

Source: Human TNF-beta Protein, His Tag (TNB-H52H3) is expressed from human 293 cells (HEK293). It contains AA Leu 35 - Leu 205 (Accession # P01374).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Leu 35 - Leu 205.

Conjugate: Unconjugated.

Molecular Weight: 20.5 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 20.5 kDa. The protein migrates as 26-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT