Description
Human TGFR-1 / ALK-5 / TGF-beta receptor type-1 Protein, Llama IgG2b Fc Tag (SPR verified) | TG1-H5259-100ug| Gentaur Distribution US, UK & Europe
TGF type I receptor also called the activin receptor-like kinase 5 (ALK5) and involved in TGF signaling. TGFβ signaling is mediated by the interaction of TGFβ ligands (TGFβ 1, 2 or 3) with cell surface receptors, the TGF type I, type II and type III receptors. Signaling is initiated by binding of TGF to the TGF type II receptor forming a ligand-receptor complex which interacts with the TGF type I receptor.
Source: Human TGF-beta RI Protein, Llama IgG2b Fc Tag (TG1-H5259) is expressed from human 293 cells (HEK293). It contains AA Leu 34 - Leu 126 (Accession # P36897-1).
Format: Powder.
Tag: C-LlamaFc (LlamaIgG2b).
Expression System: HEK293.
Expression Region: Leu 34 - Leu 126.
Conjugate: Unconjugated.
Molecular Weight: 38.0 kDa.
Characteristics: This protein carries a llama IgG2b Fc tag at the C-terminus. The protein has a calculated MW of 38.0 kDa. The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: 51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5.
Storage Conditions: -20℃.
Shipping Conditions: RT