Human TGF-beta RI Protein, Fc Tag (MALS verified) | TG1-H5254-100ug

Human TGF-beta RI Protein, Fc Tag (MALS verified) | TG1-H5254-100ug| Gentaur Distribution US, UK & Europe

TGF type I receptor also called the activin receptor-like kinase 5 (ALK5) and involved in TGF signaling. TGFβ signaling is mediated by the interaction of TGFβ ligands (TGFβ 1, 2 or 3) with cell surface receptors, the TGF type I, type II and type III receptors. Signaling is initiated by binding of TGF to the TGF type II receptor forming a ligand-receptor complex which interacts with the TGF type I receptor.

Source: Human TGF-beta RI Protein, Fc Tag (TG1-H5254) is expressed from human 293 cells (HEK293). It contains AA Leu 34 - Leu 126 (Accession # P36897-1).

Format: Powder.

Tag: C-Fc.

Expression System: HEK293.

Expression Region: Leu 34 - Leu 126.

Conjugate: Unconjugated.

Molecular Weight: 36.7 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 36.7 kDa. The protein migrates as 43-48 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT