Description
Human TGF-beta 3 / TGFB3 Protein, premium grade | TG3-H5213-1mg| Gentaur Distribution US, UK & Europe
Transforming growth factor beta 3 ( TGFB3) is also known as TGF-β3, is a polypeptide member of the transforming growth factor beta superfamily of cytokines. It is a secreted protein that performs many cellular functions, including regulates embryogenesis and cell differentiation and is required in various processes such as secondary palate development. TGF-beta 3 is similar with TGF-beta 1 and -beta 2, act as cellular switches to regulate immune function, cell proliferation, and epithelial-mesenchymal transition. TGF-beta-3 is released from LAP by integrins: integrin-binding results in distortion of the LAP chain and subsequent release of the active TGF-beta-3. Once activated following release of LAP, TGF-beta-3 acts by binding to TGF-beta receptors (TGFBR1 and TGFBR2), which transduce signal.
Source: Human TGF-beta 3, premium grade (TG3-H5213) is expressed from human 293 cells (HEK293). It contains AA Ala 301 - Ser 412 (Accession # P10600-1).
Format: Powder.
Tag: Native.
Expression System: HEK293.
Expression Region: Ala 301 - Ser 412.
Conjugate: Unconjugated.
Molecular Weight: 12.7 kDa.
Characteristics: This protein carries no "tag". The protein has a calculated MW of 12.7 kDa. The protein migrates as 12 kDa under reducing (R) condition (SDS-PAGE).
Purity: 95%.
Buffer: 50 mM HAC, pH2.8.
Storage Conditions: -20℃.
Shipping Conditions: RT
