Human Tau-441 GSK-3beta-phosphorylated protein, His Tag | TAU-H5147-50ug

Human Tau-441 GSK-3beta-phosphorylated protein, His Tag | TAU-H5147-50ug| Gentaur Distribution US, UK & Europe

Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

Source: Human Tau-441 GSK-3beta-phosphorylated protein, His Tag (TAU-H5147) is expressed from E. coli cells. It contains AA Met 1 - Leu 441 (Accession # P10636-8).

Format: Liquid.

Tag: N-10×His.

Expression System: E. coli.

Expression Region: Met 1 - Leu 441.

Conjugate: Unconjugated.

Molecular Weight: 47.9 kDa.

Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 47.9 kDa. The protein migrates as 45-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

Purity: 90%.

Buffer: 50 mM Tris, 150 mM NaCl, pH7.5.

Storage Conditions: -70℃.

Shipping Conditions: Dry ice