Human Tau-441 / 2N4R Pre-formed Fibrils Protein, Tag Free (ThT active) | TAU-H5115-500ug

Human Tau-441 / 2N4R Pre-formed Fibrils Protein, Tag Free (ThT active) | TAU-H5115-500ug| Gentaur Distribution US, UK & Europe

Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome 17q21. Tau Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) can result in the self-assembly of tangles of paired helical filaments and straight filaments, which are involved in the pathogenesis of Alzheimer's disease, frontotemporal dementia, and other tauopathies.

Source: Human Tau-441 Pre-formed Fibrils, Tag Free (TAU-H5115) is expressed from E.coli cells. It contains AA Met 1 - Leu 441 (Accession # P10636-8).

Format: Liquid.

Tag: Native.

Expression System: E. coli.

Expression Region: Met 1 - Leu 441.

Conjugate: Unconjugated.

Molecular Weight: 45.8 kDa.

Characteristics: This protein carries no "tag". The protein has a calculated MW of 45.8 kDa.

Purity: 95%.

Buffer: 50 mM Tris, 150 mM NaCl, 1 mM DTT, 1 mM EDTA, pH7.5.

Storage Conditions: -70℃.

Shipping Conditions: Dry ice