Human Plasma Kallikrein / KLKB1 Protein, His Tag (active enzyme, MALS verified) | KL1-H52H9-500ug

Human Plasma Kallikrein / KLKB1 Protein, His Tag (active enzyme, MALS verified) | KL1-H52H9-500ug| Gentaur Distribution US, UK & Europe

Human Plasma Kallikrein, a serine protease, is synthesized in the liver and circulates in the plasma by binding to high molecular weight (HMW) kininogen or as a free zymogen. The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.

Source: Human Plasma Kallikrein/KLKB1, His Tag (KL1-H52H9) is expressed from human 293 cells (HEK293). It contains AA Gly 20 - Ala 638 (Accession # P03952-1).

Format: Liquid.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Gly 20 - Ala 638.

Conjugate: Unconjugated.

Molecular Weight: 71.1 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 71.1 kDa. The protein migrates as 70-90 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: 50mM Tris 150mM NaCl, PH7.5.

Storage Conditions: -70℃.

Shipping Conditions: Dry ice