Description
Human Plasma Kallikrein / KLKB1 Protein, His Tag (active enzyme, MALS verified) | KL1-H52H9-500ug| Gentaur Distribution US, UK & Europe
Human Plasma Kallikrein, a serine protease, is synthesized in the liver and circulates in the plasma by binding to high molecular weight (HMW) kininogen or as a free zymogen. The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.
Source: Human Plasma Kallikrein/KLKB1, His Tag (KL1-H52H9) is expressed from human 293 cells (HEK293). It contains AA Gly 20 - Ala 638 (Accession # P03952-1).
Format: Liquid.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Gly 20 - Ala 638.
Conjugate: Unconjugated.
Molecular Weight: 71.1 kDa.
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 71.1 kDa. The protein migrates as 70-90 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 95%.
Buffer: 50mM Tris 150mM NaCl, PH7.5.
Storage Conditions: -70℃.
Shipping Conditions: Dry ice
