Human PADI6 Protein, His Tag | PA6-H5545-1mg

Human PADI6 Protein, His Tag | PA6-H5545-1mg| Gentaur Distribution US, UK & Europe

This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes.

Source: Human PADI6 Protein, His Tag (PA6-H5545) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Pro 694 (Accession # Q6TGC4).

Format: Liquid.

Tag: N-10×His.

Expression System: InsectCells.

Expression Region: Met 1 - Pro 694.

Conjugate: Unconjugated.

Molecular Weight: 79.7 kDa.

Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 79.7 kDa. The protein migrates as 80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: 50mM Tris, 150mM NaCl, pH7.5.

Storage Conditions: -70℃.

Shipping Conditions: Dry ice