Human MICA (24-309) Protein, Fc Tag (MALS verified) | MIA-H5254-1mg

Human MICA (24-309) Protein, Fc Tag (MALS verified) | MIA-H5254-1mg| Gentaur Distribution US, UK & Europe

MHC class I polypeptide-related sequence A (MICA) belongs to the MHC class I family and MIC subfamily. MICA contains one Ig-like C1-type (immunoglobulin-like) domain. Unlike classical MHC class I molecules, MICA does not form a heterodimer with beta-2-microglobulin. MICA acts as a stress-induced self-antigen that is recognized by gamma delta T-cells. MICA is ligand for the KLRK1/NKG2D receptor. MICA bind to KLRK1 leads to cell lysis.

Source: Human MICA (24-309) Protein, Fc Tag (MIA-H5254) is expressed from human 293 cells (HEK293). It contains AA Glu 24 - Thr 309 (Accession # Q29983-1).

Format: Powder.

Tag: C-Fc.

Expression System: HEK293.

Expression Region: Glu 24 - Thr 309.

Conjugate: Unconjugated.

Molecular Weight: 59.4 kDa.

Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 59.4 kDa. The protein migrates as 80-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT