Human MAdCAM-1 Protein, His Tag (MALS & SPR verified) | MAM-H52H4-1mg

Human MAdCAM-1 Protein, His Tag (MALS & SPR verified) | MAM-H52H4-1mg| Gentaur Distribution US, UK & Europe

The mucosal addressin cell adhesion molecule-1 (MAdCAM-1) takes a key role in the endothelial adhesion and migration of lymphocytes to sites of inflammation in inflammatory disease. In vitro and in vivo data indicate that blockade of the adhesion molecule mucosal address in cell adhesion molecule (MAdCAM) pathway decreases leukocyte homing to the gut by inhibiting the interaction between MAdCAM and its ligand the α4β7 integrin expressed on lymphocytes.

Source: Human MAdCAM-1, His Tag (MAM-H52H4) is expressed from human 293 cells (HEK293). It contains AA Gln 19 - Gln 317 (Accession # Q13477-1).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Gln 19 - Gln 317.

Conjugate: Unconjugated.

Molecular Weight: 33.3 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 33.3 kDa. The protein migrates as 46-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT