Human M-CSF / CSF-1 Protein, premium grade | MCF-H5218-1mg

Human M-CSF / CSF-1 Protein, premium grade | MCF-H5218-1mg| Gentaur Distribution US, UK & Europe

The colony stimulating factor 1 (CSF1), also known as macrophage colony-stimulating factor (M-CSF), is a secreted cytokine which influences hematopoietic stem cells to differentiate into macrophages or other related cell types. Eukaryotic cells also produce M-CSF in order to combat intercellular viral infection. It is one of the three experimentally described colony-stimulating factors. M-CSF binds to the colony stimulating factor 1 receptor. Macrophage colony-stimulating factor has been shown to interact with PIK3R2. M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. Locally produced M-CSF in the vessel wall contributes to the development and progression of atherosclerosis.

Source: Human M-CSF Protein, premium grade (MCF-H5218) is expressed from human 293 cells (HEK293). It contains AA Glu 33 - Arg 255 (Accession # P09603-1).

Format: Powder.

Tag: Native.

Expression System: HEK293.

Expression Region: Glu 33 - Arg 255.

Conjugate: Unconjugated.

Molecular Weight: 25.1 kDa.

Characteristics: This protein carries no "tag". The protein has a calculated MW of 25.1 kDa. The protein migrates as 35-45 kDa under reducing (R) condition, and 50-58 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT