Human HLA-A*11:01&B2M&KRASG12V (VVVGAVGVGK) Tetramer Protein | HLV-H52H9-200ug

Human HLA-A*11:01&B2M&KRASG12V (VVVGAVGVGK) Tetramer Protein | HLV-H52H9-200ug| Gentaur Distribution US, UK & Europe

The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention. The Human HLA-A*1101 KRASG12V (VVVGAVGVGK) complex protein is a complex of HLA-A*1101 of the MHC Class I, B2M, and VVVGAVGVGK peptide of the KRASG12V.

Source: Human HLA-A*11:01&B2M&KRASG12V (VVVGAVGVGK) Tetramer Protein (HLV-H52H9) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Thr 305 (HLA-A*11:01) & Ile 21 - Met 119 (B2M) & VVVGAVGVGK peptide (Accession # Q5S3G3-1 (HLA-A*11:01) & P61769 (B2M) & VVVGAVGVGK).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Gly 25 - Thr 305 (HLA-A*11:01) & Ile 21 - Met 119 (B2M) & VVVGAVGVGK peptide.

Conjugate: Unconjugated.

Molecular Weight: 36.0 kDa and 11.7 kDa.

Characteristics: Human HLA-A*11:01&B2M&KRASG12V (VVVGAVGVGK) Tetramer Protein is assembled by biotinylated monomer (HLV-H82E7) and streptavidin. Biotinylated Human HLA-A*11:01&B2M&KRASG12V (VVVGAVGVGK) Complex Protein is produced by co-expression of HLA and B2M loaded with KRASG12V peptide. Biotinylated Human HLA-A*11:01&B2M&KRASG12V (VVVGAVGVGK) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 36.0 kDa and 11.7 kDa. The protein migrates as 41-43 kDa, 13 kDa and 10 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT