Description
Human HLA-A*11:01&B2M&KRASG12V (VVGAVGVGK) Tetramer Protein | HLV-H52H8-200ug| Gentaur Distribution US, UK & Europe
The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention. The Biotinylated Human HLA-A*1101 KRASG12V (VVGAVGVGK) complex protein is a complex of HLA-A*1101 of the MHC Class I, B2M, and VVGAVGVGK peptide of the KRASG12V.
Source: Human HLA-A*11:01&B2M&KRASG12V (VVGAVGVGK) Tetramer Protein (HLV-H52H8) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Thr 305 (HLA-A*11:01) & Ile 21 - Met 119 (B2M) & VVGAVGVGK peptide (Accession # Q5S3G3-1 (HLA-A*11:01) & P61769 (B2M) & VVGAVGVGK).
Format: Powder.
Tag: C-10×His.
Expression System: HEK293.
Expression Region: Gly 25 - Thr 305 (HLA-A*11:01) & Ile 21 - Met 119 (B2M) & VVGAVGVGK peptide.
Conjugate: Unconjugated.
Molecular Weight: 36.0 kDa and 11.7 kDa.
Characteristics: Human HLA-A*11:01&B2M&KRASG12V (VVGAVGVGK) Tetramer Protein is assembled by biotinylated monomer and streptavidin. Biotinylated Human HLA-A*11:01&B2M&KRASG12V (VVGAVGVGK) Complex Protein is produced by co-expression of HLA and B2M loaded with KRASG12V peptide. Biotinylated Human HLA-A*11:01&B2M&KRASG12V (VVGAVGVGK) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 36.0 kDa and 11.7 kDa. The protein migrates as 39-43 kDa, 14 kDa and 12 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: PBS, pH7.4.
Storage Conditions: -20℃.
Shipping Conditions: RT
