Human HLA-A*03:01&B2M&KRASG12C (VVVGACGVGK) Complex Protein (Monomer, MALS verified) | HLC-H52H5-200ug

Human HLA-A*03:01&B2M&KRASG12C (VVVGACGVGK) Complex Protein (Monomer, MALS verified) | HLC-H52H5-200ug| Gentaur Distribution US, UK & Europe

The Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) oncogene plays a critical role in the initiation and maintenance of pancreatic tumors and its signaling network represents a major target for therapeutic intervention. The Human HLA-A*0301 KRASG12C (VVVGACGVGK) complex protein is a complex of HLA-A*0301 of the MHC Class I, B2M, and VVVGACGVGK peptide of the KRASG12C.

Source: Human HLA-A*03:01&B2M&KRASG12C (VVVGACGVGK) Complex Protein (HLC-H52H5) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Thr 305 (HLA-A*03:01) & Ile 21 - Met 119 (B2M) & VVVGACGVGK peptide (Accession # P04439 (HLA-A*03:01) & P61769 (B2M) & VVVGACGVGK).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Gly 25 - Thr 305 (HLA-A*03:01) & Ile 21 - Met 119 (B2M) & VVVGACGVGK peptide.

Conjugate: Unconjugated.

Molecular Weight: 34.2 kDa and 11.7 kDa.

Characteristics: Human HLA-A*03:01&B2M&KRASG12C (VVVGACGVGK) Complex Protein is produced by co-expression of HLA and B2M loaded with KRASG12C peptide. This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 34.2 kDa and 11.7 kDa. The protein migrates as 37-40 kDa and 8 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT