Description
Human GSK-3beta / GSK-3β Protein, His Tag (active enzyme, HPLC verified) | GSB-H5545-20ug| Gentaur Distribution US, UK & Europe
Glycogen synthase kinase-3 (GSK-3) is a pivotal molecule in the development of Alzheimer's disease (AD). GSK-3beta is involved in the formation of paired helical filament (PHF) -tau, which is an integral component of the neurofibrillary tangle (NFT) deposits that disrupt neuronal function, and a marker of neurodegeneration in AD.
Source: Human GSK-3beta, His Tag (GSB-H5545) is expressed from Baculovirus-Insect cells. It contains AA Met 1 - Thr 420 (Accession # P49841-1).
Format: Liquid.
Tag: N-10×His.
Expression System: InsectCells.
Expression Region: Met 1 - Thr 420.
Conjugate: Unconjugated.
Molecular Weight: 48.8 kDa.
Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 48.8 kDa. The protein migrates as 49-53 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: 50 mM Tris, 150 mM NaCl, pH7.5.
Storage Conditions: -70℃.
Shipping Conditions: Dry ice
