Human CXCL13 / BCA-1 Protein, His Tag | CX3-H1249-1mg

Human CXCL13 / BCA-1 Protein, His Tag | CX3-H1249-1mg| Gentaur Distribution US, UK & Europe

CXCL13, originally known as BLC (B-lymphocyte chemoattractant) or BCA-1 (B cell-attracting chemokine 1), is a homeostatic chemokine. It is constitutively secreted by stromal cells in B-cell areas of secondary lymphoid tissues (follicles), such as spleen, lymph nodes, tonsils, and Peyer's patches. CXCL13 plays a key role in orchestrating cell migration within spatially distinct regions of the secondary lymphoid organs. It strongly attracts B lymphocytes while promoting migration of only small numbers of T cells and macrophages. CXCL13 exerts its functions through its receptor CXCR5, which initially, was isolated from Burkitt Lymphoma and therefore designated as Burkitt's lymphoma receptor 1 (BLR1).

Source: Human CXCL13 Protein, His Tag (CX3-H1249) is expressed from E. coli cells. It contains AA Val 23 - Pro 109 (Accession # O43927-1).

Format: Powder.

Tag: N-10×His.

Expression System: E. coli.

Expression Region: Val 23 - Pro 109.

Conjugate: Unconjugated.

Molecular Weight: 12.2 kDa.

Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 12.2 kDa. The protein migrates as 12-15 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT