Human Coagulation factor VII / F7 Protein, His Tag (active enzyme, MALS verified) | TF7-H52H5-100ug

Human Coagulation factor VII / F7 Protein, His Tag (active enzyme, MALS verified) | TF7-H52H5-100ug| Gentaur Distribution US, UK & Europe

Coagulation factor VII is also known as F7, SPCA and Proconvertin. Heterodimer of a light chain and a heavy chain linked by a disulfide bond. Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.

Source: Human Coagulation factor VII, His Tag (TF7-H52H5) is expressed from human 293 cells (HEK293). It contains AA Ala 61 - Pro 466 (Accession # P08709-1).

Format: Powder.

Tag: C-10×His.

Expression System: HEK293.

Expression Region: Ala 61 - Pro 466.

Conjugate: Unconjugated.

Molecular Weight: 47.1 kDa.

Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 47.1 kDa. The protein migrates as 50-60 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 95%.

Buffer: 50 mM Tris, 150 mM NaCl, pH7.5.

Storage Conditions: -20℃.

Shipping Conditions: RT