Human CD19-coupled Magnetic Beads | MBS-K005-10mg

Human CD19-coupled Magnetic Beads | MBS-K005-10mg| Gentaur Distribution US, UK & Europe

Chimeric antigen receptors (CARs) comprise interact domains, of which target cancer cell expressed antigens and allow T cell to efficiently kill the cancer cell. FMC63 is an IgG2a mouse monoclonal antibody specific for CD19, which is a target for the immunotherapy of B lineage leukaemias and lymphomas. FMC63 scFv is the most commonly used ectodomain component of CD19-specific CARs. Our CAR-like cells apply the HEK293 cells for the expression of FMC63 which will be presented on the cell membrane. It mimics the real CAR-T cell reaction and it is used as positive control for Anti-CD19 scFv Antibody flow cytometry detection.

Source: Human CD19 protein is expressed from human 293 cells (HEK293) . It contains AA Pro 20 - Lys 291 (Accession # P15391-1) .

Molecule: CD19.

Format: Powder.

Species: Human.

Application: This product is intended for immunocapture, biopanning and flow cytometry. This product is produced non-sterile.

Kit Component: Antibody Purification: 1. Resuspend the lyophilized beads by adding the buffer of choice. 2. Add analyte to the suspension, mix and incubate to enable specific binding of the beads and the target protein. 3. Magnetize beads, remove supernatant, and wash unbound protein fractions to capture target protein-bound beads. 4. Wash, magnetize the beads and collect purified target protein for use in downstream applications.

Stability: Upon receipt, please store the Beads at -20°C. The shelf life is 1 year at -20 °C. Once reconstitution, please aliquote and store under -70°C for no more than 3 months, and avoid repeated freeze-thaw cycles. Immediate use after reconstitution is highly recommended. Please avoid more than 3 freeze-thaw cycles. Immediate use after reconstitution is highly recommended.

Storage Conditions: -20℃, aviod light.

Shipping Conditions: RT