Human Cadherin-17 / CDH17 Protein, Mouse IgG1 Fc Tag | CA7-H52A9-1mg

Human Cadherin-17 / CDH17 Protein, Mouse IgG1 Fc Tag | CA7-H52A9-1mg| Gentaur Distribution US, UK & Europe

Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.

Source: Human Cadherin-17 Protein, Mouse IgG1 Fc Tag (CA7-H52A9) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Met 787 (Accession # Q12864-1).

Format: Powder.

Tag: C-mFc (mIgG1).

Expression System: HEK293.

Expression Region: Gln 23 - Met 787.

Conjugate: Unconjugated.

Molecular Weight: 111.2 kDa.

Characteristics: This protein carries a mouse IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 111.2 kDa. The protein migrates as 130-135 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: 20 mM Tris, 150 mM NaCl, pH8.0.

Storage Conditions: -20℃.

Shipping Conditions: RT