Description
Human Cadherin-17 / CDH17 Protein, Fc Tag | CA7-H5258-1mg| Gentaur Distribution US, UK & Europe
Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.
Source: Human Cadherin-17 Protein, Fc Tag (CA7-H5258) is expressed from human 293 cells (HEK293). It contains AA Gln 23 - Met 787 (Accession # Q12864-1).
Format: Powder.
Tag: C-Fc.
Expression System: HEK293.
Expression Region: Gln 23 - Met 787.
Conjugate: Unconjugated.
Molecular Weight: 111.4 kDa.
Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 111.4 kDa. The protein migrates as 43-95 kDa and 130-150 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Purity: 90%.
Buffer: 20 mM Tris, 150 mM NaCl, pH8.0.
Storage Conditions: -20℃.
Shipping Conditions: RT
