Human B7-H3 (4Ig) -coupled Magnetic Beads | MBS-K040-2mg

Human B7-H3 (4Ig) -coupled Magnetic Beads | MBS-K040-2mg| Gentaur Distribution US, UK & Europe

B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.

Source: Human B7-H3 Protein is expressed from human 293 cells (HEK293) . It contains AA Gly 27 - Thr 461 (Accession # Q5ZPR3-1) .

Molecule: B7-H3.

Format: Powder.

Species: Human.

Application: This product is intended for immunocapture, biopanning and flow cytometry. This product is produced non-sterile.

Kit Component: Antibody Purification: 1. Reconstitute the beads with ultrapure water to 1 mg/mL, and wash the beads for three times. 2. Dilute the biotinalyted protein or antibodies with Assay Buffer and add to the beads. Incubate for 60 minutes at room temperature in a rotary mixer. 3. Wash the beads for four times, and add Assay Buffer to the beads. The beads are ready to use for the next experiment.

Stability: Upon receipt, please store the beads at -20°C for 1 year in lyophilized state. Please avoid more than 3 freeze-thaw cycles. Immediate use after reconstitution is highly recommended.

Storage Conditions: -20℃, aviod light.

Shipping Conditions: RT