Granzyme B Antibody | RQ5315

Granzyme B Antibody | RQ5315 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol

Format: Purified

Clone: AAHC-7

Host Animal: Rabbit

Clonality: Rabbit Monoclonal

Species Reactivity: Human

Application: IHC-P

Buffer: N/A

Limitation: This Granzyme B antibody is available for research use only.

Purity: Affinity purified

Description: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Immunogen: A synthetic peptide specific to human Granzyme B / GZMB was used as the immunogen for the Granzyme B antibody.

Storage: Store the Granzyme B antibody at -20 °C.