Description
Granzyme B Antibody | RQ5315 | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol
Format: Purified
Clone: AAHC-7
Host Animal: Rabbit
Clonality: Rabbit Monoclonal
Species Reactivity: Human
Application: IHC-P
Buffer: N/A
Limitation: This Granzyme B antibody is available for research use only.
Purity: Affinity purified
Description: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Immunogen: A synthetic peptide specific to human Granzyme B / GZMB was used as the immunogen for the Granzyme B antibody.
Storage: Store the Granzyme B antibody at -20 °C.
