Glucocorticoid Receptor Polyclonal Antibody | E-AB-70157

Glucocorticoid Receptor Polyclonal Antibody | E-AB-70157 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB, IHC

Research Area: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Background: This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. This receptor is typically found in the cytoplasm, but upon ligand binding, is transported into the nucleus. It is involved in inflammatory responses, cellular proliferation, and differentiation in target tissues. Mutations in this gene are associated with generalized glucocorticoid resistance. Alternative splicing of this gene results in transcript variants encoding either the same or different isoforms.

Lead Time: 7~10 days

Concentration: 1.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant proteincorresponding to Mouse Glucocorticoid receptor

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification: Affinity purification

Dilution: WB 1:500-1:1000, IHC 1:500-1:1000

Conjugation: Unconjugated

Calculated Molecular Weight: 91 kDa

Observed Molecular Weight: 91 kDa

Clonality: Polyclonal