GHR Antibody / Growth Hormone Receptor | RQ5338

GHR Antibody / Growth Hormone Receptor | RQ5338 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Antibody in PBS with 0.02% sodium azide and 50% glycerol

Format: Purified

Clone: 17G57

Host Animal: Rabbit

Clonality: Rabbit Monoclonal

Species Reactivity: Human, Mouse

Application: WB

Buffer: N/A

Limitation: This GHR antibody is available for research use only.

Purity: Affinity purified

Description: The GHR gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene. [RefSeq]

Immunogen: A synthetic peptide specific to human Growth Hormone Receptor / GHR was used as the immunogen for the GHR antibody.

Storage: Store the GHR antibody at -20 °C.