GABAA Receptor alpha1 Polyclonal Antibody | E-AB-70290

GABAA Receptor alpha1 Polyclonal Antibody | E-AB-70290 | Gentaur US, UK & Europe Disrtribition

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Application: WB

Research Area: Cancer, Neuroscience

Background: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene

Lead Time: 7~10 days

Concentration: 0.73 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: KLH conjugated Synthetic peptide corresponding to mouse GABA A Receptor alpha 1

Buffer: PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification: Affinity purification

Dilution: WB 1:500-1:2000

Conjugation: Unconjugated

Calculated Molecular Weight: 52 kDa

Observed Molecular Weight: 52 kDa

Clonality: Polyclonal