FOXP2 Antibody | F53693-0.1ML

FOXP2 Antibody | F53693-0.1ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: In ascites with 0.09% sodium azide

Format: Ascites

Clone: 533CT26.1.2

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: WB, ELISA

Buffer: N/A

Limitation: This anti-FOXP2 antibody is available for research use only.

Purity: Ascites

Description: This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.

Immunogen: A portion of amino acids 657-684 from the human protein was used as the immunogen for this anti-FOXP2 antibody.

Storage: Aliquot the anti-FOXP2 antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.