Flotillin 2 Antibody | R31143

Flotillin 2 Antibody | R31143 | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: 0.5mg/ml if reconstituted with 0.2ml sterile DI water

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Species Reactivity: Human, Mouse, Rat

Application: WB

Buffer: N/A

Limitation: This Flotillin 2 antibody is available for research use only.

Purity: Antigen affinity

Description: Flotillin 2, also known as ESA1 or M17S1, is a protein that in humans is encoded by the FLOT2 gene. Schroeder et al.(1991) isolated a cDNA for an epidermal surface antigen believed to be involved in epidermal cell adhesion. By analysis of a somatic cell hybrid panel and in situ hybridization using the FLOT2 cDNA, the gene was mapped to 17q11-q12 in the region containing the NF1 gene. Bickel et al.(1997) found that mouse Flot2 consistently copurifies with Flot1 and with caveolin-1 in the purification of caveolin-rich membranes. Using a quantitative proteomic analysis of cultured mouse neuronal stem cells, Li et al.(2012) found that palmitoylation and oligomerization of Flotillin2 was abolished in homozygous Dhhc5 mutant neuronal stem cells. The absolute amount of Flotillin2 was not changed in Dhhc5 mutant neurons.

Immunogen: An amino acid sequence from the N-terminus of human FLOT2 (TLTVEQIYQDRDQFA) was used as the immunogen for this Flotillin 2 antibody (100% homologous in human, mouse and rat).

Storage: After reconstitution, the Flotillin 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 °C. Avoid repeated freezing and thawing.