eGFP NK-92 Cell Line | 78399

eGFP NK-92 Cell Line | 78399 | Gentaur US, UK & Europe Disrtribition

Category: Immunotherapy/Cell Line

Application: Use as a control for NK cell killing assays Use as a platform to generate Chimeric Antigen Receptor-modified Natural Killer Cells (CAR-NK)

Background: T cells expressing Chimeric Antigen Receptors (CARs) have shown promising results in targeting antigen-specific tumor cells. However, CAR-T cell therapy comes with specific risks such as Graft versus Host Disease or cytokine storm. Natural Killer (NK) cells are also cytotoxic to cancer cells and can make a good alternative to CAR-T with lesser risk or side effects. NK-92 cells are a human Interleukin-2 (IL-2)-dependent NK cell line derived from a patient with non-Hodgkin's lymphoma. NK-92 cells can be used to generate Chimeric Antigen Receptor-modified Natural Killer cells (CAR-NK).

Description: Recombinant stable NK-92 cell line constitutively expressing enhanced Green Fluorescent Protein (eGFP). The cell line was generated using the eGFP Lentivirus ( BPS Bioscience #79979). Expression is driven by a CMV promoter.

Product Type: Cell Line

Shippement Condition: -80°C