Description
DRAM Antibody | N1206-25UG | Gentaur US, UK & Europe Disrtribition
Family: Primary antibody
Formulation: 0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Format: Purified
Clone: N/A
Host Animal: Rabbit
Clonality: Polyclonal (rabbit origin)
Species Reactivity: Human, Mouse, Rat
Application: WB
Buffer: 1X PBS, pH 7.4
Limitation: This DRAM antibody is available for research use only.
Purity: Protein A affinity chromatography
Description: Autophagy is the mechanism by which lysosomes degrade unneeded or dysfunctional cellular components. p53 is a tumor suppressor protein that modulates autophagy and apoptosis. DRAM, or damage regulated autophagy modulator, is a lysosomal protein and effector of p53-mediated cell death. Many tumors show decreased DRAM expression and siRNA knockdown resulted in reduced cell death (Crighton et al, 2006).
Immunogen: A recombinant protein fragment from the N-terminal region of human DRAM was used as the immunogen for this antibody.
Storage: Aliquot the DRAM antibody and store frozen at -20 °C or colder. Avoid repeated freeze-thaw cycles.
