Cytokeratin 8/18 Antibody | V3316-0.5ML

Cytokeratin 8/18 Antibody | V3316-0.5ML | Gentaur US, UK & Europe Disrtribition

Family: Primary antibody

Formulation: Bioreactor concentrate with 0.05% sodium azide

Format: Bioreactor concentrate

Clone: 5D3

Host Animal: Mouse

Clonality: Monoclonal (mouse origin)

Species Reactivity: Human

Application: FACS, IF, IHC-P

Buffer: N/A

Limitation: This Cytokeratin 8/18 antibody is available for research use only.

Purity: Unpurified high titer supernatant

Description: Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This mAb recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.

Immunogen: A cytoskeleton preparation from human breast cancer MCF-7 cells was used as the immunogen for the Cytokeratin 8/18 antibody.

Storage: Store the Cytokeratin 8/18 antibody at 2-8oC.