Cynomolgus LIGHT / TNFSF14 Protein, His Tag, active trimer (MALS verified) | LIT-C5244-100ug

Cynomolgus LIGHT / TNFSF14 Protein, His Tag, active trimer (MALS verified) | LIT-C5244-100ug| Gentaur Distribution US, UK & Europe

Tumor necrosis factor ligand superfamily member 14 (LIGHT) is a tumor necrosis factor (TNF) superfamily ligand that regulates T cell immune responses by signaling through the herpes virus entry mediator (HVEM) and the lymphotoxin beta receptor (LTbetaR). LIGHT has emerged as a potent initiator of T cell co-stimulation signals effecting CTL-mediated tumor rejection, allograft rejection and graft versus host disease. Constitutive expression of LIGHT leads to tissue destruction and autoimmune-like disease syndromes.

Source: Cynomolgus LIGHT Protein, His Tag (LIT-C5244) is expressed from human 293 cells (HEK293). It contains AA Asp 74 - Val 240 (Accession # E9NVF7).

Format: Powder.

Tag: N-10×His.

Expression System: HEK293.

Expression Region: Asp 74 - Val 240.

Conjugate: Unconjugated.

Molecular Weight: 58.6 kDa.

Characteristics: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 58.6 kDa. The protein migrates as 63-66 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Purity: 90%.

Buffer: PBS, pH7.4.

Storage Conditions: -20℃.

Shipping Conditions: RT